疾病自然疗法
分享&收藏溃疡性结肠炎自然疗法
溃疡性结肠炎 (Ulcerative colitis) 是一种累及结肠的疾病,与克罗恩病关系非常密切。两者均为消化道的炎症反应,因此统称为炎症性肠病 (IBD)。
溃疡性结肠炎的临床症状主要是腹痛和血便,有时亦可出现便秘。当疾病严重时也可出现发热、消瘦、脱水和贫血等症状。关节炎、皮肤溃疡和肝炎等也时有发生。溃疡性结肠炎最严重的后果是结肠急剧膨胀,这可能引起结肠穿孔而危及生命。溃疡性结肠炎还会增加发生结肠癌的风险。

溃疡性结肠炎的病情时轻时重,有明显的缓解期和发病期之分。治疗的目的主要是缓解症状、控制发病期以及维持缓解期。柳氮磺吡啶是最常用于治疗溃疡性结肠炎的一种药物,它既可以口服也可以灌肠使用,这种药物能够同时减轻症状和预防复发。皮质类固醇类药物 (如强的松等) 常用于更加严重的情况,它们有时可以与硫唑嘌呤、环孢霉素等免疫抑制剂合用。对于病情严重的患者有时还需要进行部分结肠切除术。
可能有效的自然疗法包括:
- 营养补充剂: 溃疡性结肠炎患者容易缺乏多种营养元素。长期的出血可以导致身体缺铁。另外,长期的肠胃吸收不良、食欲下降、药物副反应以及经大便流失的营养成分都会引起轻重不等的营养缺乏,包括蛋白质、维生素A、B12、C、D、E、K、叶酸、钙、铜、镁、硒和锌等的缺乏。如果您患有溃疡性结肠炎,那么补充这些营养成分是十分重要的,这不仅能改善疾病的临床症状,而且有益于全身的健康状况。
- 必需脂肪酸: 鱼油和月见草油 (Evening primrose oil) 中含有对人体有益的必需脂肪酸。据一部分小规模的双盲研究报道,鱼油可能有利于减轻溃疡性结肠炎发病期的症状。月见草油也有相似的功效。不过它们的疗效还需要更大规模的研究来证实。

参考文献
- Striola GC, Restrainer C, Lecis PE, et al. Altered plasma and mucosal concentrations of trace elements and antioxidants in active ulcerative colitis. Scand J Gastroenterol. 1998;33:644-649.
- Mortensen PB, Abildgaard K, Fallingborg J. Serum selenium concentration in patients with ulcerative colitis. Dan Med Bull. 1989;36:568-570.
- Dronfield MW, Malone JD, Langman MJ. Zinc in ulcerative colitis: a therapeutic trial and report on plasma levels. Gut. 1977;18:33-36.
- Elsborg L, Larsen L. Folate deficiency in chronic inflammatory bowel disease. Scand J Gastroenterol. 1979;14:1019-1024.
- Krasinski SD, Russell RM, Furie BC, et al. The prevalence of vitamin K deficiency in chronic gastrointestinal disorders. Am J Clin Nutr. 1985;41:639-643.
- Bischoff SC, Herrmann A, Goke M, et al. Altered bone metabolism in inflammatory bowel disease. Am J Gastroenterol. 1997;92:1157-1163.
- Dibble JB, Sheridan P, Losowsky MS. A survey of vitamin D deficiency in gastrointestinal and liver disorders. Q J Med. 1984;53:119-134.
- Mulder TP, van der Sluys Veer A, Verspaget HW, et al. Effect of oral zinc supplementation on metallothionein and superoxide dismutase concentrations in patients with inflammatory bowel disease. J Gastroenterol Hepatol. 1994;9:472-477.
- Ainley CC, Cason J, Carlsson LK, et al. Zinc status in inflammatory bowel disease. Clin Sci (Colch). 1988;75:277-283.
- Halsted CH, Ghandi G, Tamura T. Sulfasalazine inhibits the absorption of folates in ulcerative colitis. N Engl J Med. 1981;305:1513-1517.
- Aslan A, Triadafilopoulos G. Fish oil fatty acid supplementation in active ulcerative colitis: a double-blind, placebo-controlled, crossover study. Am J Gastroenterol. 1992;87:432-437.
- Almallah YZ, El-Tahir A, Heys SD, et al. Distal procto-colitis and n-3 polyunsaturated fatty acids: the mechanism(s) of natural cytotoxicity inhibition. Eur J Clin Invest. 2000;30:58-65.
- Stenson WF, Cort D, Rodgers J, et al. Dietary supplementation with fish oil in ulcerative colitis. Ann Intern Med. 1992;116:609-614.
- Hawthorne AB, Daneshmend TK, Hawkey CJ, et al. Treatment of ulcerative colitis with fish oil supplementation: a prospective 12-month randomised controlled trial. Gut. 1992;33:922-928.
- Greenfield SM, Green AT, Teare JP, et al. A randomized controlled study of evening primrose oil and fish oil in ulcerative colitis. Aliment Pharmacol Ther. 1993;7:159-166.
- Greenfield SM, Green AT, Teare JP, et al. A randomized controlled study of evening primrose oil and fish oil in ulcerative colitis. Aliment Pharmacol Ther. 1993;7:159-166.
- Rembacken BJ, Snelling AM, Hawkey PM, et al. Non-pathogenic Escherichia coli versus mesalazine for the treatment of ulcerative colitis: a randomised trial. Lancet. 1999;354:635-639.
- Faubion WA, Sandborn WJ. Probiotic therapy with E. coli for ulcerative colitis: take the good with the bad. Gastroenterology. 2000;118:630-631.
- Gionchetti P, Rizzello F, Venturi A, et al. Oral bacteriotherapy as maintenance treatment in patients with chronic pouchitis: a double-blind, placebo-controlled trial. Gastroenterology. 2000;119:305-309.
- Candy S, Borok G, Wright JP, et al. The value of an elimination diet in the management of patients with ulcerative colitis. S Afr Med J. 1995;85:1176-1179.
- Gionchetti P, Rizzello F, Helwig U, et al. Prophylaxis of pouchitis onset with probiotic therapy: a double-blind, placebo-controlled trial. Gastroenterology. 2003;124:1202-1209.
- Langmead L, Feakins RM, Goldthorpe S, et al. Randomized, double-blind, placebo-controlled trial of oral aloe vera gel for active ulcerative colitis. Aliment Pharmacol Ther. 2004;19:739-748.
- Kato K, Mizuno S, Umesaki Y, et al. Randomized placebo-controlled trial assessing the effect of bifidobacteria-fermented milk on active ulcerative colitis. Aliment Pharmacol Ther. 2004;20:1133-1141.
- Karimi O, Pena AS, van Bodegraven AA, et al. Probiotics (VSL#3) in arthralgia in patients with ulcerative colitis and Crohn's disease: A pilot study. Drugs Today (Barc). 2005;41:453-459.
- Hanai H, Iida T, Takeuchi K, et al. Curcumin maintenance therapy for ulcerative colitis: randomized, multicenter, double-blind, placebo-controlled trial. Clin Gastroenterol Hepatol. 2006 Nov 10. [Epub ahead of print]
- Mallon P, McKay D, Kirk S, et al. Probiotics for induction of remission in ulcerative colitis. Cochrane Database Syst Rev. 2007 Oct 17;CD005573.


